Biology

DNA Replication – Leading Strand vs Lagging Strand & Okazaki Fragments

This biology video tutorial provides a basic introduction into DNA replication. It discusses the difference between the leading strand and the lagging strand as well as the presence of okazaki fragments.

Here is a list of topics:
0:00 – Intro to DNA Replication
0:00 – Semiconservative Replication
0:49 – DNA strands are antiparallel
1:07 – Complementary Base Pairing In DNA
2:05 – Hydrogen Bonds Between Adenine, Thymine, Cytosine, and Guanine In DNA
2:39 – Bidirectionality of DNA and Origin of Replication
3:26 – DNA Helicase and Topoisomerase
4:30 – Single Stranded Binding (SSB) Proteins
4:53 – RNA Primers and Primase
5:27 – DNA Polymerase III
5:49 – Semidiscontinuous Nature of DNA Replication
6:40 – Leading Strand and Lagging Strand
9:00 – Okazaki Fragments
9:13 – The Function of DNA Ligase
9:30 – Exonuclease Activity of DNA Polymerase I and III – Proofreading Ability and DNA Repair